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Breast Cancer News

In this section, access cutting-edge metastatic breast cancer news on treatment updates, emerging therapies, study results and other medical and quality-of-life issues important to you.

Advanced breast cancer inching up in young women

NEW YORK (Reuters Health) - More young women are being diagnosed with advanced, metastatic breast cancer than were three decades ago, a new study suggests - although the overall rate of cancers in that group is still small.

FDA OKs Roche drug for late-stage metastatic breast cancer

(Reuters) - U.S. health regulators approved a new drug made by Roche Holding AG for some patients with late-stage metastatic breast cancer who fail to respond to other therapies.

T-DM1 Overall Survival Data Released, FDA Grants Priority Review

An article in the New England Journal of Medicine with updated overall survival results from the international EMILIA study of T-DM1 was published two days following an announcement of accelerated FDA review for the medicine.

Higher Dose of Fulvestrant May Increase Survival

Findings from the CONFIRM clinical trial presented at the 2012 San Antonio Breast Cancer Symposium in December showed that increasing the dose of fulvestrant (Faslodex) from 250 mg to 500 mg for women with estrogen receptor-positive metastatic breast cancer increased median overall survival by 4.1 months. Overall survival is the time a person lives from the start of treatment until death from any cause.

Progression-Free, Overall Survival Improves with Anastrozole and Fulvestrant

In a study published in The New England Journal of Medicine, researchers suggest that anastrozole (Arimidex), taken in combination with fulvestrant (Faslodex), extends both progression-free and overall survival in hormone receptor-positive metastatic breast cancer.

Lapatinib Plus Trastuzumab Impacts Overall Survival

A final data analysis of the study EGF104900, which compared lapatinib (Tykerb) plus trastuzumab (Herceptin) to lapatinib alone, found the combination therapy resulted in a significant increase in overall survival in women with HER2 positive metastatic breast cancer.

Bevacizumab Does Not Impact Overall Survival, Quality of Life

A new report indicates that the use of bevacizumab (Avastin) in the treatment of women with metastatic breast cancer slows the progression of the disease but has no impact on their overall survival, the length of time women live after receiving treatment, or on their quality of life.

Good Dental Hygiene May Help Prevent Osteonecrosis

New evidence suggests that osteonecrosis of the jaw is uncommon after treatment with bisphosphonates or denosumab (Xgeva), a lab-created protein used to prevent bone fractures in cancers that metastasized to the bone. Monitoring oral dental health may prevent or resolve osteonecrosis as a side effect, the study found.

T-DM1 Delays Time to Progression and Extends Survival

Results from the international EMILIA study suggest a new effective treatment for HER2 positive metastatic breast cancer, using trastuzumab (Herceptin) linked with the potent chemotherapy DM1.

Everolimus Gains FDA Approval for Metastatic Breast Cancer

Postmenopausal women with metastatic, hormone receptor-positive breast cancer may now be treated with everolimus (Afinitor) in combination with exemestane (Aromasin), following FDA’s recent approval of the tablet medicine.

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