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Breast Cancer News

In this section, access cutting-edge breast cancer news on treatment updates, emerging therapies, study results and other medical and quality-of-life issues important to you.

ASCO Issues First Guidelines for Metastatic HER2-positive Breast Cancer

To help doctors recommend treatment options based on research evidence and expert consensus, the American Society of Clinical Oncology released its first guidelines on treating metastatic HER2-positive breast cancer.

ASCO issued two clinical practice guidelines for this breast cancer type. One advises on systemic (whole body) therapies for HER2-positive breast cancer that has advanced outside of the breast, other than to the brain. The other recommends specifics on treating brain metastases.

ASCO Reports on Early-Stage Breast Cancers

LBBC highlights two studies reported on the last day of the annual meeting of the American Society of Clinical Oncology: GeparSixto, which looked at the impact of adding a platinum chemotherapy to standard medicines given before surgery to people with triple-negative breast cancer and a family history of breast or ovarian cancer; and an analysis of the PAM50 genomic assay as a tool to help people with early-stage breast cancer make decisions about mastectomy versus lumpectomy and radiation. 

Targeted Therapies Heat up Oncology Meeting

Sunday reports from the 50th annual meeting of the American Society of Clinical Oncology focused on using aromatase inhibitors in premenopausal women with early-stage, estrogen-positive breast cancer and on a negative study of lapatinib for HER2-positive early-stage disease. 

ASCO Studies Focus on Premenopausal Women

Researchers announced findings from breast cancer studies during Saturday’s sessions of the 50th Annual Meeting of the American Society of Clinical Oncology, in Chicago. Today's reports focus on obesity and risk of recurrence in pre- and peri-menopausal women; preserving fertility in young women taking chemotherapy; and the future of bevacizumab (Avastin) in breast cancer. 

Should Low Estrogen Receptor Status Be Considered Positive?

Breast cancers with a low level of estrogen receptor positivity – only 1 to 9 percent of tumor cells being positive – is more similar to ER-negative disease than to breast cancer with ER positivity of 10 percent or greater, according to a recent study. 

African-Americans More Likely to Stop Working During Early Breast Cancer Treatment, Study Suggests

African-American women were more likely to stop working during the first 2 months of breast cancer treatment compared with non-Hispanic white peers, an analysis found. The study, published in Journal of Cancer Survivorship, assessed racial differences in quality of life and employment after breast cancer diagnosis.

Women With Young Children Less Likely to Receive Radiation Therapy

Having very young children may affect whether women receive radiation therapy after breast-conserving surgery.

ASCO Releases Updated Sentinel Lymph Node Biopsy Guidelines

The American Society of Clinical Oncology published updates to their 2005 guidelines for use of sentinel lymph node biopsy in early-stage breast cancer. The guidelines, based on the review of 9 randomized clinical trials and 13 cohort studies, reflect what ASCO believes are best practices in using the biopsy.

Study Suggests What May Influence Black Women’s Breast Cancer-Related Distress

Trust in medical care received, age, and positive attitude are factors that may affect risk for anxiety or depression among black women newly diagnosed with breast cancer, researchers found. 

Everolimus Plus Exemestane — A Possible First-Line Therapy for Metastatic Disease

Everolimus (Afinitor) and exemestane (Aromasin) taken at the same time may be an effective first-line treatment for hormone receptor-positive breast cancer that spread beyond the breast to other organs, after treatment with another aromatase inhibitor. This finding comes from a new analysis of data from the BOLERO-2 trial. 

Denver, CO  ·  September 13, 2014

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