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Featured Clinical Trials

Learn what’s coming down the research pipeline, and find breast cancer clinical trials you may be eligible to participate in.

Trial Tests Antidepressant as Therapy for Treatment-Related Joint Pain

Researchers seek postmenopausal women with hormone-positive breast cancer for a clinical trial exploring whether daily doses of an antidepressant lessens pain related to the use of hormonal therapies, when compared to women who take no pain medicines.

Trial Tests Hormonal Therapy With and Without Chemo for Early-Stage, Invasive Breast Cancer

Researchers seek women diagnosed with invasive, early-stage, hormone-positive breast cancer to enroll in a phase III study. 

Trial Seeks Participants With Metastatic Breast Cancer and BRCA1/2 Mutations

The BROCADE study needs men and women with metastatic breast cancer and a BRCA1 or BRCA2 gene mutation for a phase II clinical trial. The trial team will assess how safe and effective a new targeted therapy is when combined with one or more common chemotherapy medicines.

Women With Metastatic Triple-Negative Breast Cancer Needed for Trial

Researchers seek 240 women with metastatic, triple-negative breast cancer for a phase II study assessing the safety of different chemotherapy combinations and how well they prevent the worsening of the disease. 

BELLE-2 Study Explores Use of PI3K Inhibitor

Postmenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer that continued to grow during or after treatment with an aromatase inhibitor (anastrozole, letrozole, and exemestane) are needed for a clinical trial. Researchers conducting the trial are examining the safety and effectiveness of combining the PI3K inhibitor BMK120 with fulvestrant (Faslodex).

Participants With HER2-Negative, Metastatic Breast Cancer Sought for Vaccine Trial

Baltimore-based researchers seek participants with metastatic breast cancer for a phase II trial comparing a combination of chemotherapy plus a cancer vaccine with or without trastuzumab.

Vaccine Designed to Prevent or Delay Recurrence, Under Study

Researchers are recruiting 700 women with HER2-negative breast cancer for an international clinical trail assessing disease-free survival (DFS), the length of time during which participants show no signs of cancer, when treated with NeuVax, a cancer vaccine designed to prevent or delay disease recurrence.

Trial Compares Radiation Therapy Regimens Given After Lumpectomy

A study for women with early-stage breast cancer removed by lumpectomy compares the safety and effectiveness of a more rapid course of radiation with standard therapy.

Combination Treatment for HER2 Metastatic Cancer under Study

Researchers seek women with metastatic, HER2 positive breast cancer for a clinical trial that will test a new combination treatment. 

Trial Examines Treatment Combination for Metastatic Breast Cancer

Researchers seek women with ER positive, HER2 negative metastatic breast cancer for a clinical trial that will test letrozole in combination with a new medicine.