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Study Will Use Breast Cells to Predict Breast Cancer Risk

Researchers seek women between the ages of 20 and 80 at high risk or average risk of developing breast cancer to donate breast tissue that will be studied over time

Trial Starts: 12/17/2007

Written By Mary Alice Hartsock

Sponsored By: National Cancer Institute

Researchers seek 110 women to donate breast tissue samples for a research study that will examine how changes in breast cancer cells may help predict breast cancer risk.

The samples will be used to establish a repository, or a facility in which tissue samples can be preserved and stored for many years. By studying the cell lines, or collections of cells grown from the original tissue, researchers hope to learn more about how certain changes in breast cells encourage these cells to develop into cancer.

Who Is Eligible to Participate?

Researchers hope to recruit ten women without an identified risk of developing breast cancer and up to 100 women at high risk. To be eligible, you must be a female between the ages of 20 and 80 with one of the following risk factors:

  • A strong family history of breast or ovarian cancer
  • Have had breast cancer in one or both breasts
  • Have had radiation for lymphoma before age 30
  • Tested positive for a gene that increases risk of developing breast cancer such as BRCA1 or BRCA2, even if your family history is unknown
  • Do not have an increased risk of developing breast cancer

You are not eligible to participate if you:

  • Have had chemotherapy within three weeks prior to the breast biopsy procedure Are pregnant
  • Have a white blood count under 2,000 or a platelet count under 50,000
  • Have an infection of any kind
  • Have had whole breast radiation therapy on both breasts
  • Have a lump or lesion of the breast discovered by physical examination or mammography

What Will I Do if I Participate?

You will have a minor surgery in which a physician will take a small piece of breast tissue. Your tissue will be stored in a repository and studied for cell changes. To learn more about participating in the study or your eligibility, call (888) NCI-1937.

Learn more about this study on breast cell lines and cancer risk.

For more information, contact: (888) 624-1937