Toremifene Citrate

Updated 
August 31, 2015
Reviewed By: 

Toremifene citrate is a hormonal therapyinfo-icon that is FDAinfo-icon approved to treat hormone receptorinfo-icon-positive metastaticinfo-icon breast cancer. It is a SERMinfo-icon, or selective estrogen receptor modulatorinfo-icon, a medicineinfo-icon that prevents estrogeninfo-icon signals from getting to breast cancer cells. They are given as daily pills.

How Toremifene Citrate Works

Toremifene citrate is closely related to tamoxifeninfo-icon. Like tamoxifen, it works by blocking estrogeninfo-icon from reaching estrogen receptors on breast cancer cells. Without the estrogen, the cancer cells can’t grow as well as they can with it.

Who Gets Toremifene Citrate

Toremifene citrate may be given if you have hormone receptorinfo-icon-positive metastaticinfo-icon breast cancer.

It is not used often in the United States, but toremifene citrate is an FDAinfo-icon approved treatment for metastatic breast cancer. Outside the U.S., this medicineinfo-icon is used for both early-stageinfo-icon and metastatic disease.

How Toremifene Citrate Is Given

Toremifene citrate is given as a daily pill. Because your body makes estrogeninfo-icon every day, it’s important to take toremifene citrate every day.

Side Effects and Things to Remember

Common side effects of toremifene citrate are:

Less common side effects of toremifene citrate are:

  • Heart problems
  • Eye problems
  • Blood clots
  • Liver problems

Toremifene citrate can cause changes in your heart rhythm, so let your doctors know if you have a history of irregular heartbeat.

Your doctor, pharmacist or nurse can help you manage your side effects. You can also go to our section on Side Effects for more information.

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