Ado-Trastuzumab Emtansine (Kadcyla)
Ado-trastuzumab emtansine is an antibody-drug conjugate, a treatment that pairs a chemotherapy medicine with a targeted therapy. The trastuzumab helps deliver the chemotherapy directly to the tumor cells. This helps limit the side effects of the chemotherapy on the healthy cells.
Common side effects of ado-trastuzumab emtansine include
- bone and joint pain
- diarrhea or constipation
- liver problems
- low platelet count, which may result in bruising
- low potassium levels
- low red blood cell count, which may result in fatigue and weakness
- nausea or stomach ache
- neuropathy, tingling or numbness in the hands or feet
Some people who take ado-trastuzumab emtansine develop a low white blood count, which may put you at risk for infection. Call your doctor right away if you show any symptoms of infection, such as a fever with chills.
If you have serious side effects, your doctor may stop treatment for a time or switch you to another treatment.
Before starting ado-trastuzumab emtansine, tell your doctor about any history of heart or lung problems as well as any medicines you are taking, including vitamins, herbal supplements and over-the-counter medicines. You should not become pregnant while taking ado-trastuzumab emtansine.