Nikhil Wagle, MD

Nikhil Wagle, MD, is an assistant professor of medicine at Harvard Medical School, a medical oncologist at Dana-Farber Cancer Institute, and an associate member of the Broad Institute of MIT and Harvard. He is the deputy director of the Center for Cancer Precision Medicine at Dana-Farber Cancer Institute. 

Dr. Wagle leads a translational research program in the field of breast cancer genomics and precision (or “personalized”) cancer medicine. The major goals of his work are to better understand the biology of metastatic breast cancer and to develop new ways to overcome or prevent medicine resistance in people with advanced breast cancer. His ultimate goal is to identify characteristics of tumors that might improve clinical decision making for people with advanced breast cancer.

Dr. Wagle leads The Metastatic Breast Cancer Project, mbcproject.org, a nationwide research initiative that seeks to empower people with advanced breast cancer around the U.S. to fast-track cancer research by sharing their tumor samples and clinical information. The project’s outreach program, developed in collaboration with advocacy organizations and people with metastatic breast cancer, serves to connect patients around the country with metastatic breast cancer research, allowing them to participate regardless of where they live.

Dr. Wagle has received several awards and honors, including a Young Investigator Award from the Conquer Cancer Foundation of the American Society of Clinical Oncology, the 2013 Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine, and the inaugural 2016 AACR NextGen Award for Transformative Cancer Research. His work has been published in the New England Journal of Medicine, the Journal of Clinical Oncology, Cancer Discovery, and Nature Medicine.