Carboplatin
Carboplatin (Paraplatin
) is a platinum-based chemotherapy
. Carboplatin and similar medicines contain the metal platinum, and are used to treat many types of cancer.
How Carboplatin Works
Carboplatin kills cancer cells by damaging their DNA and stopping them from dividing.
Who Gets Carboplatin
Carboplatin may be used to treat metastatic breast cancer. It can also be used with the chemotherapy
medicines docetaxel
(Taxotere
) or paclitaxel
(Taxol
) and the targeted therapy trastuzumab
(Herceptin
) after surgery
as adjuvant treatment for HER2-positive breast cancers, in the regimen
called TCH.
You may be offered carboplatin as part of a clinical trial. Researchers are looking at the benefits of using carboplatin to treat specific types of breast cancer, including breast cancer that has developed because of a BRCA gene
mutation
.
How Carboplatin Is Given
Carboplatin is taken by vein
. It is usually given every 3 weeks, though how often you receive carboplatin and the total number of cycles depends on your situation.
Side Effects
Different medicines have different side effects. You may not have every side effect related to each medicine
. Side effects of carboplatin
include:
- Decrease of white blood cells
- Neuropathy, or tingling in the hands and feet
- Fatigue
- Hair loss or thinning
- Kidney damage
- Nausea and vomiting
Be sure to tell your doctor about any medicines you are taking, including vitamins, herbal supplements and over-the counter-medicines, to make sure they will not interfere with your chemotherapy treatment.
While you are taking carboplatin, drink lots of fluids to avoid kidney side effects. Ask your doctor how much and how often you should drink each day.
Seek immediate medical care if you have chills or a fever of 100.5 degrees Fahrenheit or higher, which may be signs of infection.
Talk to your doctor, pharmacist or nurse
about all your side effects so that they can help you manage them. You can also go to our section on Side Effects for more information.