Eribulin (Halaveninfo-icon) is a microtubule inhibitor chemotherapyinfo-icon that was first made from a sea sponge. It is used to treat metastatic breast cancer.

Eribulin was FDAinfo-icon approved in November 2010 based on results of the EMBRACE trial. This study showed women who took eribulin lived an average of 3 months longer than those who received a different chemotherapy of their doctor’s choice.

How Eribulin Works

Eribulin works by blocking cancer cellinfo-icon growth by stopping mitosis, the process of cells dividing. It interferes with the growth phase of microtubules, the structures of the cell that help move information inside cells during mitosis.

How Eribulin Is Given

Eribulin is usually taken on its own. It is given by veininfo-icon, usually once a week for 2 weeks, followed by 1 week off. You and your doctor will discuss how many cycles you will have.

Side Effects and Things to Remember

Side effects may include:

Before starting eribulin, be sure to tell your doctor about any medicines you are taking, including vitamins, herbal supplements and over-the-counterinfo-icon medicines. Let your healthcare team know if you have heart or kidney problems.

You should avoid becoming pregnant while you are receiving eribulin. Tell your doctor right away if you become pregnant or may be pregnant while you are undergoing treatment.

Your doctor, pharmacistinfo-icon or nurseinfo-icon can help you manage your side effects. You can also go to our section on Side Effects for more information.

August 31, 2015
Reviewed By: