About Us > Steven J. Chmura, MD, PhD

Steven J. Chmura, MD, PhD


  • Scientific director of the cancer clinical trials office at the University of Chicago Comprehensive Cancer Center
  • Served as director of Clinical and Translational Research for Radiation Oncology at the University of Chicago for over a decade

Dr. Chmura has been actively involved in both the clinical implementation of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). His main interests and research focus on translational and clinical trial development in the developmental therapeutics space.

Dr. Chmura is a leader in the NCI cooperative groups and has led to the first international trials through NRG Oncology studying the safety of treating oligometastatic patients and the ongoing Phase II/III trial studying possible improvements to progression-free survival and overall survival in patients with oligometastatic breast cancer through the use of SBRT. His work in radio-immunology has also translated into multiple trials along with the NCI-sponsored trial randomizing the role of SBRT combined with pembrolizumab in advanced Merkel cell carcinoma. Integrating radiotherapy and immunotherapy in such cases, along with advancing the search for biomarkers, is currently Dr. Chmura's focus.